Welcome to Netbiz

So you have an idea for an online business?

If you've ever thought about establishing your own online business now is the time to do something about it. All you need is one good idea. We will help with the rest. Think of us as a one-stop shop where you'll get all the advice you need to get you started in business and be successful enough to stay there!

Call us now for a free initial consultation. We cover everything you need know about online business so you can make up your mind as to whether it's worthwhile going ahead with your idea. Let us help you:-

  • Discover if your idea is "do-able" (after we sign a confidentiality agreement)
  • Turn your idea into a money-making business
  • Find a suitable structure for your new online business
  • Create a domain name for your business and help you register it
  • Create a website that you can maintain yourself. You know how to use a wordprocessor?
  • Create your own eCommerce site with the ability to sell product and put money into your bank account
  • Get your domain listed in google
  • Get your office going at the lowest cost by demonstrating the options you have that others won't tell you about!
  • Get your telephone, fax, internet and mobile phone connected at the lowest cost and the biggest bang for your dollar
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There is new syndicated content from JAMA -- Medical Informatics: Improving Health Care Through ....

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  • PDOException: SQLSTATE[22001]: String data, right truncated: 1406 Data too long for column 'author' at row 1: INSERT INTO {aggregator_item} (title, link, author, description, guid, timestamp, fid) VALUES (:db_insert_placeholder_0, :db_insert_placeholder_1, :db_insert_placeholder_2, :db_insert_placeholder_3, :db_insert_placeholder_4, :db_insert_placeholder_5, :db_insert_placeholder_6); Array ( [:db_insert_placeholder_0] => Association Between BRCA1 and BRCA2 Mutations and Survival in Women With Invasive Epithelial Ovarian Cancer [Original Contribution] [:db_insert_placeholder_1] => http://jama.ama-assn.org/cgi/content/short/307/4/382?rss=1 [:db_insert_placeholder_2] => Bolton, K. L., Chenevix- Trench, G., Goh, C., Sadetzki, S., Ramus, S. J., Karlan, B. Y., Lambrechts, D., Despierre, E., Barrowdale, D., McGuffog, L., Healey, S., Easton, D. F., Sinilnikova, O., Benitez, J., Garcia, M. J., Neuhausen, S., Gail, M. H., Hartge, P., Peock, S., Frost, D., Evans, D. G., Eeles, R., Godwin, A. K., Daly, M. B., Kwong, A., Ma, E. S. K., Lazaro, C., Blanco, I., Montagna, M., D'Andrea, E., Nicoletto, M. O., Johnatty, S. E., Kjaer, S. K., Jensen, A., Hogdall, E., Goode, E. L., Fridley, B. L., Loud, J. T., Greene, M. H., Mai, P. L., Chetrit, A., Lubin, F., Hirsh-Yechezkel, G., Glendon, G., Andrulis, I. L., Toland, A. E., Senter, L., Gore, M. E., Gourley, C., Michie, C. O., Song, H., Tyrer, J., Whittemore, A. S., McGuire, V., Sieh, W., Kristoffersson, U., Olsson, H., Borg, A., Levine, D. A., Steele, L., Beattie, M. S., Chan, S., Nussbaum, R. L., Moysich, K. B., Gross, J., Cass, I., Walsh, C., Li, A. J., Leuchter, R., Gordon, O., Garcia-Closas, M., Gayther, S. A., Chanock, S. J., Antoniou, A. C., Pharoah, P. D. P., for the EMBRACE, kConFab Investigators, and The Cancer Genome Atlas Research Network [:db_insert_placeholder_3] => <p><b>Context</b> Approximately 10% of women with invasive epithelial ovarian cancer (EOC) carry deleterious germline mutations in <I>BRCA1</I> or <I>BRCA2</I>. A recent article suggested that <I>BRCA2</I> -related EOC was associated with an improved prognosis, but the effect of <I>BRCA1</I> remains unclear.</p> <p><b>Objective</b> To characterize the survival of <I>BRCA</I> carriers with EOC compared with noncarriers and to determine whether <I>BRCA1</I> and <I>BRCA2</I> carriers show similar survival patterns.</p> <p><b>Design, Setting, and Participants</b> A pooled analysis of 26 observational studies on the survival of women with ovarian cancer, which included data from 1213 EOC cases with pathogenic germline mutations in <I>BRCA1</I> (n&nbsp;=&nbsp;909) or <I>BRCA2</I> (n&nbsp;=&nbsp;304) and from 2666 noncarriers recruited and followed up at variable times between 1987 and 2010 (the median year of diagnosis was 1998).</p> <p><b>Main Outcome Measure</b> Five-year overall mortality.</p> <p><b>Results</b> The 5-year overall survival was 36% (95% CI, 34%-38%) for noncarriers, 44% (95% CI, 40%-48%) for <I>BRCA1</I> carriers, and 52% (95% CI, 46%-58%) for <I>BRCA2</I> carriers. After adjusting for study and year of diagnosis, <I>BRCA1</I> and <I>BRCA2</I> mutation carriers showed a more favorable survival than noncarriers (for <I>BRCA1</I>: hazard ratio [HR], 0.78; 95% CI, 0.68-0.89; <I>P</I>&nbsp;&lt;&nbsp;.001; and for <I>BRCA2</I>: HR, 0.61; 95% CI, 0.50-0.76; <I>P</I>&nbsp;&lt;&nbsp;.001). These survival differences remained after additional adjustment for stage, grade, histology, and age at diagnosis (for <I>BRCA1</I>: HR, 0.73; 95% CI, 0.64-0.84; <I>P</I>&nbsp;&lt;&nbsp;.001; and for <I>BRCA2</I>: HR, 0.49; 95% CI, 0.39-0.61; <I>P</I>&nbsp;&lt;&nbsp;.001). The <I>BRCA1</I> HR estimate was significantly different from the HR estimated in the adjusted model (<I>P</I> for <I></I> heterogeneity&nbsp;=&nbsp;.003).</p> <p><b>Conclusion</b> Among patients with invasive EOC, having a germline mutation in <I>BRCA1</I> or <I>BRCA2</I> was associated with improved 5-year overall survival. <I>BRCA2</I> carriers had the best prognosis.</p> [:db_insert_placeholder_4] => [:db_insert_placeholder_5] => 1327438549 [:db_insert_placeholder_6] => 39 ) in aggregator_save_item() (line 153 of /home/netbla5/public_html/modules/aggregator/aggregator.processor.inc).